Clinical Studies


The pH of the skin surface and its impact on the barrier function.

Departments of Dermatology and Allergology, Rheinische Friedrich Wilhelm University, Bonn, Germany.

Effects of soap and detergents on skin surface pH, stratum corneum hydration and fat content in infants 

Department of Pediatrics, University of Vienna, School of Medicine, Austria.

Measurement of skin pH.

Unit of Cell Pharmacology, School of Pharmacy, Israel.

Skin pH: from basic science to basic skin care.

Saba M. AlI and Gil Yosipovitch Department of Dermatology, Wake Forest University Baptist Medical Center, Winston-Salem, USA

Correlation between pH and irritant effect of cleansers marketed for dry skin.

Servicio de Dermatología Hospital Central Ignacio Morones Prieto, San Luis Potosí, México.

Progression of temporary into persistent facial wrinkling: An 8-year longitudinal study.

G.G. Hillebrand, Z. Liang,* X. Yan* and T. Yoshii The Procter & Gamble Company, Cincinnati, OH 45241, U.S.A.

A Guide to the Ingredients and Potential Benefits of Over-The-Counter Cleansers and Moisturizers for Rosacea Patients

Jacquelyn Levin, Do; Richard Miller; Do Largo Medical Center, Largo, Florida; bNova Southeastern University College of Osteopathic Medicine and Largo Medical Center, Largo, Florida

The alkaline pH-adapted skin barrier is disrupted severely by SLS-induced irritation.

Skin Research Institute, R&D Center, Amore Pacific Corporation, 314-1, 446-729 Bora-dong Giheung-gu Yongin-Si Gyeonggi-do, Korea.

Natural skin surface pH is on average below 5, which is beneficial for its resident flora.

Sara Lee Household and Body Care Research, Fruitweg, The Hague, The Netherlands.

Effect of skin pH for wrinkle formation on Asian: Korean, Vietnamese and Singaporean.

 Amorepacific Corporation R&D Center, 314-1, Bora-dong Giheung-gu Yongin-si Gyeonggi-do, 446-729, Korea Division of Chemical Engineering, College of Engineering, Hanyang University, Seoul

Treatment of Aged Skin with a pH 4 Skin Care Product Normalizes Increased Skin Surface pH and Improves Barrier Function: Results of a Pilot Study.

 Department of Dermatology, Environmental Medicine and Health Theory, University of Osnabrück, Osnabrück, Germany; 2Research and Development, Kneipp-Werke, Würzburg, Germany. Email:


An Updated Review of Tyrosinase Inhibitors

2009 Department of Biological Science and Technology, National University of Tainan, 33 sec. 2 Shu-Lin St., Tainan, Taiwan; E-Mail:; Tel. +886 6 2606283; Fax: +886 6 2909502

Anti-angiogenic effects of epigallocatechin-3-gallate in human skin

2010 1University Hospitals Case Medical Center, Departments of Dermatology, Cleveland, OH 44106, USA

Innovations in natural ingredients and their use in skin care.

2010 University of Louisville, Division of Dermatology, Louisville, KY 40202, USA.

Pharmacological Review on Centella asiatica: A Potential Herbal Cure-all

2010 Department of Pharmacology, Maliba Pharmacy College, Bardoli-394 350, India Department of Pharmacology, Institute of Pharmacy, Nirma University (NU), Ahmedabad-382 481, India

The polyhydroxy acid gluconolactone protects against ultraviolet radiation in an in vitro model of cutaneous photoaging.

 2004 DakDak Photoaging Technologies, Division of Charles River Laboratories, Inc., Pennsylvania College of Optometry, Elkins Park KGL Inc., Ivy Laboratories University City Science Center, Philadelphia, Pennsylvania, USA.

Reduction in the appearance of facial hyperpigmentation by topical N-acetyl glucosamine.

2007 Procter & Gamble Company, Cincinnati, Ohio 45252, USA.



The Alkaline Diet: Is There Evidence That an Alkaline pH Diet Benefits Health?

2012 University of Alberta, Suite No. 301, 9509-156 Street, Edmonton, AB, Canada T5P 4J5 Gerry K. Schwalfenberg

Dietary nutrient intakes and skin-aging appearance among middle-aged American women.

2007 Corporate Research, Unilever Colworth Park, Bedford, United Kingdom.